AICAR 50mg
AICAR, also known as acadesine or 5-aminoimidazole-4-carboxamide riboside, is a synthetic adenosine analog supplied for laboratory and analytical research applications. This research compound is widely utilized in controlled experimental settings involving cellular energy regulation, metabolic signaling, glucose transport, lipid metabolism, mitochondrial activity, and responses to cellular stress.
Within cells, AICAR can be transported across the cell membrane and phosphorylated by adenosine kinase to form ZMP, an intracellular analog of adenosine monophosphate. ZMP is commonly studied for its interaction with AMP-activated protein kinase, or AMPK, a central cellular energy sensor involved in coordinating metabolic activity in response to changes in energy availability.
In controlled research environments, AICAR is frequently evaluated in studies examining AMPK-dependent signaling, glucose uptake, fatty-acid oxidation, mitochondrial biogenesis, autophagy, cellular energy balance, and metabolic adaptation. Investigational applications may also include skeletal muscle cell models, hepatocyte research, adipocyte differentiation studies, inflammatory signaling analysis, hypoxic stress models, and comparisons between AMPK-dependent and AMPK-independent cellular responses.
Because AICAR may influence additional enzymes and nucleotide-regulated pathways independently of AMPK, it is also utilized in mechanistic studies designed to distinguish direct AMPK activation from broader effects involving purine metabolism, adenosine regulation, and intracellular nucleotide balance.
Supplied in a 50 mg lyophilized presentation, AICAR is suitable for controlled in vitro research, biochemical assays, metabolic pathway investigations, and other standardized analytical workflows. Each vial is provided as a white lyophilized powder with a specified purity of ≥99%.
Specifications
Size: 50 mg
Compound Type: Synthetic nucleoside analog
Alternate Names: Acadesine, AICA riboside, 5-aminoimidazole-4-carboxamide riboside
Form: Lyophilized powder
Purity: ≥99% (target specification)
Primary Research Area: AMPK and cellular metabolic signaling
Storage: Store at -20°C away from light and moisture. Reconstitute only under appropriate laboratory conditions using standard research protocols.
Intended Use
This product is supplied strictly for laboratory research purposes only and is intended for use by qualified professionals in controlled scientific environments. It is not for human or animal consumption and is not intended for therapeutic, diagnostic, veterinary, cosmetic, athletic, or food use. All handling and use must comply with applicable institutional and regulatory guidelines.
FDA Disclaimer
The statements made on this website have not been evaluated by the U.S. Food and Drug Administration (FDA). Products offered are not intended to diagnose, treat, cure, or prevent any disease. Alamo Peptides operates solely as a supplier of research materials and analytical reagents. We are not a pharmacy, outsourcing facility, or pharmaceutical manufacturer. All products are intended exclusively for research use only. By purchasing, customers acknowledge responsibility for proper handling, use, and compliance with all applicable laws and regulations.
Terms of Sale
All sales are final due to the nature of research materials. Purchasers must be 21 years of age or older. Improper use voids any warranties. Alamo Peptides assumes no liability for misuse or improper application of supplied materials.
