SS-31 50mg
SS-31, also known as elamipretide, MTP-131, or Bendavia, is a synthetic aromatic-cationic tetrapeptide with the amino-acid sequence D-Arg–Dmt–Lys–Phe–NH₂, where Dmt represents 2,6-dimethyltyrosine. SS-31 is cell-permeable and has been extensively investigated for its ability to associate with mitochondrial membranes, particularly cardiolipin-rich regions of the inner mitochondrial membrane.
Unlike mitochondria-targeting compounds that depend primarily on mitochondrial membrane potential for accumulation, SS-31 has been studied for membrane interactions involving electrostatic and hydrophobic forces. Experimental research indicates that SS-31 interacts with cardiolipin-containing lipid bilayers and may influence membrane organization, mitochondrial cristae architecture, and the functional environment surrounding respiratory-chain proteins. The full molecular mechanism remains under investigation and may involve multiple mitochondrial lipids and proteins rather than a single isolated target.
In controlled laboratory systems, SS-31 is commonly evaluated in studies of mitochondrial respiration, oxidative phosphorylation, ATP synthesis, electron transport, reactive oxygen species formation, membrane curvature, mitochondrial protein interactions, and cellular responses to energetic or oxidative stress. Investigational models have also examined its relationship with cytochrome c activity, adenine nucleotide transport, mitochondrial morphology, cristae organization, and recovery of bioenergetic function following experimentally induced mitochondrial disruption.
SS-31 is widely used as a research tool in mitochondrial biology, cellular metabolism, aging-related bioenergetics, skeletal and cardiac muscle models, renal research, and neurological systems. Findings vary according to the experimental model, tissue type, concentration, and study design; therefore, observed effects should not be interpreted as established therapeutic outcomes.
Supplied in a 50 mg lyophilized presentation, SS-31 is suitable for analytical and investigational laboratory workflows. Each vial is provided as a lyophilized powder with purity exceeding 99% as verified by HPLC testing. Third-party analytical verification and corresponding certificates of analysis are provided where applicable.
Specifications
Size: 50 mg
Compound Type: Synthetic aromatic-cationic tetrapeptide
Sequence: D-Arg–Dmt–Lys–Phe–NH₂
Alternative Names: Elamipretide, MTP-131, Bendavia
Form: Lyophilized powder
Purity: >99% (HPLC verified)
Storage: Store at -20°C away from light and moisture. Reconstitute only under appropriate laboratory conditions using standard research protocols.
Intended Use
This product is supplied strictly for laboratory research purposes only and is intended for use by qualified professionals in controlled scientific environments. It is not for human or animal consumption and is not intended for therapeutic, diagnostic, veterinary, cosmetic, or food use. All handling and use must comply with applicable institutional and regulatory guidelines.
FDA Disclaimer
The statements made on this website have not been evaluated by the U.S. Food and Drug Administration (FDA). Products offered are not intended to diagnose, treat, cure, or prevent any disease. Alamo Peptides operates solely as a supplier of research materials and analytical reagents. We are not a pharmacy, outsourcing facility, or pharmaceutical manufacturer. All products are intended exclusively for research use only. By purchasing, customers acknowledge responsibility for proper handling, use, and compliance with all applicable laws and regulations.
Terms of Sale
All sales are final due to the nature of research materials. Purchasers must be 21 years of age or older. Improper use voids any warranties. Alamo Peptides assumes no liability for misuse or improper application of supplied materials.
