Semax 10mg

Semax 10mg – Nootropic & Neuroprotective Heptapeptide

Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a high-purity synthetic heptapeptide analog of adrenocorticotropic hormone (ACTH) fragment 4–10, supplied as a research-grade reagent for laboratory investigations into neuroprotection, cognitive function, neurotrophic factor modulation, and central nervous system stress response pathways. This modified peptide, featuring a Pro-Gly-Pro C-terminal extension for enhanced stability and resistance to enzymatic degradation, serves as a valuable tool in in vitro and preclinical models exploring neuronal survival, synaptic plasticity, BDNF/trkB signaling, dopaminergic and serotonergic modulation, and adaptive responses to ischemia, oxidative stress, and neurotoxic insults.

In published mechanistic and preclinical studies, Semax has demonstrated upregulation of brain-derived neurotrophic factor (BDNF) expression and trkB receptor phosphorylation in hippocampal models, modulation of dopaminergic and serotonergic neurotransmission, and influences on immune and vascular gene expression during focal ischemia. Additional observations include reduced inflammatory signaling and oxidative stress, improved neuronal survival under hypoxic or excitotoxic conditions, and potential effects on attention, memory formation, and neurorestorative pathways in controlled experimental systems. Semax has been utilized in research to investigate neurotrophic signaling, neuroimmune crosstalk, gene regulation in ischemic models, cognitive pathway modulation, and protective mechanisms against neurodegeneration and CNS injury.

The 10 mg lyophilized presentation is well-suited for exploratory studies, dose-response characterization, and extended experimental protocols requiring sufficient material for neuronal assays, gene expression analysis, neurotrophic pathway investigation, or ischemia-reperfusion models. Each vial is supplied as a white lyophilized powder with documented purity exceeding 99% by HPLC, verified through third-party testing and supported by certificates of analysis including mass spectrometry confirmation.

Specifications

• Quantity: 10 mg
• Form: Lyophilized powder
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: ~813.93 g/mol
• Purity: >98% (HPLC verified)
• CAS No.: 80714-61-0
• Storage: Store lyophilized vial at -20°C; protect from light and moisture. Reconstitute only in qualified laboratory settings per standard protocols.

Intended Use This peptide is supplied strictly for in vitro and laboratory research purposes only by qualified professionals in controlled scientific environments. It is not for human or animal consumption, not for therapeutic, diagnostic, veterinary, food, cosmetic, or any non-research applications. All handling must comply with institutional biosafety and regulatory guidelines.

FDA Disclaimer The information provided on this website has not been evaluated or approved by the U.S. Food and Drug Administration (FDA). None of the statements herein, nor any products offered, are intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Alamo Peptides operates solely as a chemical and research reagent supplier. We are not a compounding pharmacy, do not operate under Section 503A or 503B of the Federal Food, Drug, and Cosmetic Act, are not a pharmaceutical company, and do not conduct or support clinical trials. All products are research reagents only—not for human use. By purchasing, you confirm you are a qualified researcher and assume full responsibility for lawful handling, use, and compliance.

Terms of Sale All sales are final due to the nature of research materials. Buyers must be 21+ and verify qualifications upon request. Misuse voids any implied warranties; Alamo Peptides assumes no liability for improper application. For research use only by qualified professionals. Contact support@alamopeptides.com (or via Discord/Telegram) for COA requests or inquiries.