Semax 10mg

Semax 10mg – Nootropic & Neuroprotective Heptapeptide

Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a high-purity synthetic heptapeptide analog of adrenocorticotropic hormone (ACTH) fragment 4-10, supplied as a research-grade reagent for laboratory investigations into neuroprotection, cognitive enhancement, neurotrophic factor modulation, and brain stress response pathways. This modified peptide, featuring the Pro-Gly-Pro C-terminal extension for enhanced stability and resistance to enzymatic degradation, serves as a valuable tool in in vitro and preclinical models exploring neuronal survival, synaptic plasticity, BDNF/trkB signaling, dopaminergic/serotonergic modulation, and adaptive responses to ischemia, oxidative stress, or neurotoxic insults.

In published mechanistic and preclinical studies, Semax has demonstrated upregulation of brain-derived neurotrophic factor (BDNF) expression and trkB receptor phosphorylation in hippocampal models, enhancement of dopaminergic and serotonergic neurotransmission, modulation of immune and vascular gene expression during focal ischemia, reduced inflammation and oxidative stress, improved neuronal survival under hypoxic or glutamate-induced conditions, and potential influences on attention, memory formation, and neurorestorative processes in cell culture, rodent brain ischemia models, and other controlled experimental systems. It has been utilized in research to probe neurotrophic signaling, neuroimmune crosstalk, gene regulation in stroke models, cognitive function pathways, and protective mechanisms against neurodegeneration or brain injury.

The 10 mg lyophilized presentation is well-suited for standard exploratory studies, dose-response characterizations, extended experiments, or investigations requiring sufficient material for neuronal cell assays, gene expression analyses, neurotrophic pathway studies, or ischemia-reperfusion models. Each vial is supplied as a white lyophilized powder with documented purity exceeding 99% by HPLC, verified through third-party testing, and accompanied by certificates of analysis including mass spectrometry confirmation.

Specifications

• Quantity: 10 mg
• Form: Lyophilized powder
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: ~813.93 g/mol
• Purity: >99% (HPLC verified)
• CAS No.: 80714-61-0
• Storage: Keep lyophilized vial at -20°C; protect from light and moisture. Reconstitute only in qualified lab settings per standard protocols.

Intended Use This peptide is supplied strictly for in vitro and laboratory research purposes only by qualified professionals in controlled scientific environments. It is not for human or animal consumption, not for therapeutic, diagnostic, veterinary, food, cosmetic, or any non-research applications. All handling must comply with institutional biosafety and regulatory guidelines.

FDA Disclaimer The information provided on this website has not been evaluated or approved by the U.S. Food and Drug Administration (FDA). None of the statements herein, nor any products offered, are intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Alamo Peptides operates solely as a chemical and research reagent supplier. We are not a compounding pharmacy, do not operate under Section 503A or 503B of the Federal Food, Drug, and Cosmetic Act, are not a pharmaceutical company, and do not conduct or support clinical trials. All products are research reagents only—not for human use. By purchasing, you confirm you are a qualified researcher and assume full responsibility for lawful handling, use, and compliance.

Terms of Sale All sales are final due to the nature of research materials. Buyers must be 21+ and verify qualifications upon request. Misuse voids any implied warranties; Alamo Peptides assumes no liability for improper application. For research use only by qualified professionals. Contact support@alamopeptides.com (or via Discord/Telegram) for COA requests or inquiries.